iStent inject^® W

The iStent inject^® W Advantage

iStent inject^® W is intended to reduce intraocular pressure safely and effectively in patients diagnosed with primary open-angle glaucoma, pseudo-exfoliative glaucoma, or pigmentary glaucoma. And it’s precision-engineered to optimise stent visualisation and placement, enhance procedural predictability, and increase confidence.

Key advantages to using the device include:

MINIMAL INVASIVENESS

Implanted through a single-entry point, iStent inject^® W is implanted during cataract surgery or as a stand-alone procedure. If implanted during cataract surgery, iStent inject^® W is implanted through the incision needed for cataract surgery itself.

DESIGNED TO IMPROVE PHYSIOLOGICAL OUTFLOW

iStent inject^® W is designed to create a bypass through the primary blockage site (trabecular meshwork).

SAFETY PROFILE

iStent inject^® W is effective when implanted in conjunction with cataract surgery or as a stand-alone procedure in patients who require intraocular pressure reduction^1-3.

RAPID RECOVERY TIME

Patient recovery time is usually rapid, which allows a quick return to normal activities.

POSITIVE PATIENT OUTCOMES

In clinical studies, most patients experience a reduction in IOP and a reduction in reliance on glaucoma medication^1-3.

1. Hengerer FH. Personal Experience with Second-Generation Trabecular Micro-Bypass Stents in Combination with Cataract Surgery in Patients with Glaucoma: 3-Year Follow-up. ASCRS 2018 Presentation.
2. Samuelson TW. Randomized evaluation of the trabecular micro-bypass stent with phacoemulsification in patients with glaucoma and cataract. Ophthalmology. March 2011;118(3):459-467.
3. Voskanyan L, García-Feijoó J, Belda J, Fea A, Jünemann A, Baudouin C. “Prospective, Unmasked Evaluation of the iStent inject System for Open-Angle Glaucoma: Synergy Trial”. Adv Ther 2014; 31:189-201.

Important Safety Information »

Mechanism of Action

Delivering two preloaded trabecular micro-bypass stents with a single entry, iStent inject^® W is designed to optimise the benefits of Trabecular Micro-Bypass surgery. The iStent inject^® W device is designed to improve aqueous outflow through the natural physiological outflow pathway. When the device is implanted in the trabecular meshwork, it is designed to stent open that section of the ocular anatomy to allow aqueous humor to flow from the anterior chamber into Schlemm’s canal. A natural episcleral back pressure of 8-11 mm Hg in the trabecular meshwork reduces the risk of hypotony.¹

1. Rosenquist R, Epstein D, Melamed S, Johnson M, Grant WM. Outflow resistance of enucleated human eyes at two different perfusion pressures and different extents of trabeculectomy. Curr Eye Res. 1989;8:1233-1240.

Important Safety Information »

Watch How It Works

The iStent inject^® W Procedure

iStent inject^® W is inserted ab interno through a microincision, which may be the phaco incision if performed in conjunction with cataract surgery, and can be performed under topical anaesthesia.

Tilt the patient’s head up to 25° away from the surgeon and tilt the microscope up to 35° toward the surgeon to obtain proper anterior chamber angle viewing

Adjust the microscope (10-12x) and locate the trabecular meshwork

	Deepen the anterior chamber with a cohesive viscoelastic as needed
	Enter the eye with the inserter through a clear corneal incision and advance past the pupillary margin
	Place the trocar through the centre or slightly anterior portion of the trabecular meshwork and into the back wall of Schlemm’s canal
	Dimple the tissue enough to see a “V” when pressing on trabecular meshwork
	Squeeze the stent delivery button, but keep your finger on the stent delivery button while pulling back from the implanted stent
	Move 2 to 3 clock hours away and implant the second stent using the same technique